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Gynaecology & Obstetrics General obstetrics 378e1792

The ovarian tumor which is most likely to be associated with virilization is

A
Granulosa tumor
B
Seoli-Leydig cell tumor
C
Immature teratoma
D
Gonadoblastoma
High-Yield Explanation
Seoli-Leydig cell tumors, which represent less than 1% of ovarian tumors, may produce symptoms of virilization. Histologically, they resemble fetal testes; clinically, they must be distinguished from other functioning ovarian neoplasms as well as from tumors of the adrenal glands, since both adrenal tumors and Seoli-Leydig tumors produce androgens. Ref: Shaw&;s Textbook of Gynaecology; 16th edition; Chapter 33; Ovarian tumors

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