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Medicine Miscellaneous 37380204

All are true about Hypertrophic Cardiomyopathy except

A
Dilated ventricle
B
Increased muscle mass
C
LV outflow obstruction
D
Diastolic failure
High-Yield Explanation
(A) Dilated ventricle # Hypertrophic cardiomyopathy (HCM) is characterized by LV hypertrophy, typically of a nondilated chamber, without obvious cause, such as hypertension or aortic stenosis.> It is found in about 1 in 500 of the general population. Two features of HCM have attracted the greatest attention: Asymmetric LV hypertrophy, often with preferential hypertrophy of the interventricular septum; and A dynamic LV outflow tract pressure gradient, related to narrowing of the subaortic area.> About one-third of patients with HCM demonstrate an outflow tract pressure gradient at rest and a similar fraction develop one with provocation.> The ubiquitous pathophysiologic abnormality is diastolic dysfunction, which can be detected by Doppler tissue imaging and results in elevated LV end-diastolic pressures; the latter may be present despite a hyperdynamic, nondilated LV.

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