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Pharmacology General 36d1a9af

Mechanism of action of clomiphene citrate is ?

A
Binds to estrogen receptors & causes negative feedback at hypothalamus
B
Binds estrogen receptors & prevents negative feed back at hypothalamus
C
Binds to progesterone receptors
D
Progesterone agonist
High-Yield Explanation
Ans. is 'b' i.e., Binds estrogen receptors & prevents negative feed back at hypothalamus o Induces gonadotropin secretion (LH, FSH) by blocking estrogenic feedback inhibition on hypothalamus.

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