A 5-year-old male presented to AIIMS pediatrics OPD with a chief complaint of difficulty in climbing stairs and getting up from sitting position. There was history of maternal uncle having the same illness. On examination; there was pseudohypertrophy of calf muscle. Biopsy of the muscle was performed as shown below. What is your diagnosis?
High-Yield Explanation
Ans. (a) Duchenne muscular dystrophy*This is myopathy with X-linked inheritance suggested by same history in maternal uncle. On muscle biopsy prominent variation in size of muscle fibers can be seen.