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Pharmacology AIIMS 2019 36cbec15

All of the following can be used to decreased intraocular pressure in glaucoma except?

A
Mannitol
B
Methazolamide
C
Clonidine
D
Dexamethasone
High-Yield Explanation
Explanation- Dexamethasone is a coicosteroid. coicosteroids are contraindicated in Glaucoma , as they result in fuher increase in the intraocular pressure. Mannitol is drug of choice for acute congestive glaucoma. For acute attack of close angle glaucoma mannitol is given IV it result in considerable decrease in Intraocular pressure.Hypeonic mannitol decongest the eye by osmotic action. TOPICAL DRUGS FOR GLAUCOMA b-Adrenergic blockers a-Adrenergic agonists Prostaglandin analogues Carbonic anhydrase inhibitors Miotics Timolol Betaxolol Levobunolol Caeolol Dipivefrine Apraclonidine Brimonidine Latanoprost Travoprost Bimatoprost Dorzolamide Brinzolamide Pilocarpine Physostigmine Echothiophate Methazolamide is carbonic anhydride inhibitor and clonidine is alpha 2 agonist. These can also cause decrease in intra ocular pressure.

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