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Biochemistry General 36be970c

Norepinephrine to epinephrine conversion requires which enzyme:

A
Phenylethanolamine-N-methyltransferase
B
Transaldolase
C
Tyrosine hydroxylase
D
Alpha ketoglutarate
High-Yield Explanation
Ans:A.)Phenylethanolamine-N-methyltransferaseMethylation of norepinephrine by S-adenosyl-methionine gives epinephrine, reaction being catalysed by phenylethanolamine N-methyltransferase Phenylethanolamine N-methyltransferase (PNMT)It is an enzyme found in the adrenal medulla that conves Norepinephrine (Noradrenaline) to Epinephrine (Adrenaline).PNMT is positively influenced by coisol, which is produced in the adrenal coex.S-adenosyl-L-methionine ('SAM') is a required cofactor.

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