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Pediatrics Genetic and genetic disorders 367cad83

Neurofibromatosis 1 criteria include all except:

A
Brain tumor
B
Acoustic neuromas
C
Dysplasia of the sphenoidal and tibial bone
D
Cafe-au-lait spots
High-Yield Explanation
In Neurofibromatosis 1 (NF1), two or more of the following clinical manifestations are present: Six or more Cafe-au-lait macules Axillary and inguinal freckling Two or more iris Lisch nodules Two or more neurofibromas or 1 plexiform neurofibroma A distinctive osseous lesion such as sphenoidal and tibial dysplasia Optic gliomas A 1st degree relative with NF1 Ref: Nelson textbook of pediatrics 21st edition pgno: 3141

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