All of the following is true when one molecule of actyl CoA is oxidized by citric acid cycle except
High-Yield Explanation
ATP Generating Steps in TCA Cycle There are 3 NADH molecules generated during one cycle, each of them will give rise to 2 1/2 ATPs on oxidation by electron transpo chain (ETC); so altogether they will give 3 x 2 1/2 = 7 1/2 (7.5) high energy phosphates. The FADH2 will generate 1 1/2 molecules of ATP. In addition, one molecule of GTP (equivalent to one molecule of ATP) is formed by substrate-level phosphorylation. Hence, per turn of the cycle, 10 high energy phosphates are produced. These steps are marked in Figure 18.5 and in Table 18.1. The summary is shown in Box 18.2. Note: Recent work shows that in the electron transpo chain, NADH produces only 2.5 ATPs and FADH only 1.5 ATPs.Ref: MN Chatterjea Textbook of Medical Biochemistry, 8th Edition, Page no: 220