A newborn has hydrocephalus, chorioretinitis, intracranial calcifications, and anemia. For the mentioned clinical scenario, select the most likely diagnosis
High-Yield Explanation
Toxoplasmosis can cause symptoms similar to other congenital infections, but the combination of hydrocephalus, chorioretinitis, and intracranial calcifications is considered the "classic triad" of toxoplasma infection in a neonate. Infection usually occurs during primary infection of the mother or as a reactivation of infection in an immune-compromised host. These infants may also display symptoms similar to other congenital infections, such as anemia, a petechial rash, organomegaly, jaundice, and seizures.