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Pediatrics General 35c0a376

Which of the following is best used in the diagnosis of congenital syphilis: March 2011

A
Dark ground microscopy
B
VDRL
C
IgM FTA-ABs
D
TPI
High-Yield Explanation
Ans. C: IgM FTA-ABs A positive VDRL test has to be confirmed by fluorescent treponemal antibody absorption test (FTA-ABS) and treponema pallidum micro hemagglutination (MHA-TP) test which are specific Late Congenital syphilis: Hutchinsons triad: - Hutchinson teeth - 8th cranial nerve deafness - Interstitial keratitis Periosteitis (Higaumenakis sign) IgM FTA-Abs is best to diagnose syphilis

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