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Pharmacology Chemotherapy 35ad7fa4

Tetracyclines inhibit protein synthesis by:

A
Inhibition of initiation and misreading of mRNA
B
Binding to 30 S subunt and inhibiting the binding of aminoacyl-RNA to A site
C
Inhibiting peptidyl transferase activity
D
Inhibiting translocation
High-Yield Explanation
The tetracyclines are primarily bacteriostatic; inhibit protein synthesis by binding to 305 ribosomes in susceptible organism. Subsequent to such binding, attachment of aminoacyl-t-RNA to the mRNA-ribosomc complex is interferred with. ESSENTIALS OF MEDICAL PHARMACOLOGY page no. 734

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