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Pathology G.I.T. 35a7cc55

In carcinoma of unknown primary, if the tissue marker CDX-2 is positive, it indicates:

A
Bladder cancer
B
Gastrointestinal cancer
C
Lung cancer
D
Thyroid cancer
High-Yield Explanation
Ans. (b) Gastrointestinal cancer(Ref: Am J Surg Pathol 2003; 27:303)CDX2: Also called caudal-related homeobox gene 2, caudal type homeobox transcription factor 2Fairly specific marker of GI origin for adenocarcinomas

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