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Microbiology parasitology 358b418a

Which of the following is detected by the antigen detection test used for the diagnosis of P. Falciparum malaria

A
Circum-sporozoite protein
B
Merozoite surface antigen
C
Histidine-Rich-Protein I (HRP-I)
D
Histidine-Rich-Protein II (HRP-II)
High-Yield Explanation
A useful approach is immunodiagnosis of malaria by detection of parasite-specific antigens using monoclonal antibodies The Para-Sight-F test (BD) is a dipstick antigen capture test targeting the "histidine-rich protein-2" (HRP-2), specific for P.falciparum. The test is sensitive, specific and rapid, results being ready in ten minutes.TEXTBOOK OF MEDICAL PARASITOLOGY, CKJ PANIKER,6TH EDITION, PAGE NO 91

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