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Pharmacology Endocrinology 35699b16

Sulfonylureas act by:

A
Decreasing glucagon secretion from pancreas
B
Decreasing insulin secretion from pancreas
C
Increasing gluconeogenesis
D
Increasing insulin secretion from pancreas
High-Yield Explanation
Ans. (D) Increasing insulin secretion from pancreas(Ref: KDT 8/e p294)Sulfonylureas stimulate the release of insulin by the beta cells of the islets of Langerhans by blocking K+ channels. Glucagon secretion is also reduced by sulfonylureas, but it is a minor action.

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