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Microbiology Immunology 350153a9

B cells are processed in

A
Bone marrow
B
Liver
C
Spleen
D
Lymph nodes
High-Yield Explanation
Ans. a (Bone marrow). (Ref: Ananthnarayan, Microbiology/6th ed., 116)# B lymphocytes precursors, pro-B cells develop in the fetal liver during embryonic life and in bone marrow afterwards continuously throughout life.# Rearrangement of Ig genes takes place on their becoming preB cell, which synthesize cytoplasmic IgM.# T-cell precursors from yolk sac, fetal liver, BM, migrates to thymus during embryonic and post- natal stages.# Earliest identifiable cells of T-lineage and CD7 + pro T cells, on entering thymus became preT cells (immature).# These cells mature in extrathymic tissue and become helper/inducer T-cells, cytotoxic supressor cells.

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