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Gynaecology & Obstetrics General 34d7378c

Vitamin deficient is most commonly seen in a pregnant mother who is on phenytoin therapy for epilepsy?

A
Vitamin B6
B
Vitamin B12
C
Vitamin A
D
Folic acid
High-Yield Explanation
Phenytoin interferes with metabolism of folate and patients taking phenytoin may become deficient in folic acid. Phenytoin decreases absorption of folic acid and increases its excretion. Ref: Advanced Therapy in Epilepsy By Wheless, James W. Wheless, James Willmore, Roger A. Brumback, 2009, Page 259.

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