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Medicine General 34d4d029

A person is HBsAg positive, but Anti- HBc Ab is negative. What should he the next step?

A
Repeat test after 6 months
B
Check HBV DNA load
C
Check HBeAg, if positive sta interferon
D
Reassure patient that he does not have any disease
High-Yield Explanation
Ans: B. Check HBV DNA load(Ref Harrison 19/e p2032, 18/e p2551)Chronic Hepatitis B - Parameters:HBsAg positive; Anti- HBc Ab negative.Presence or absence of serum hepatitis Be antigen (HBeAg).HBeAg-reactive & HbeAg negative.HBV DNA level correlate with liver injury level & has progression risk.Treatment pre-requisites:HBV-DNA load should be done before initiating treatment.

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