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Medicine General 346c0a85

In multiple myeloma following are seen except:

A
Anion gap raised
B
Lytic bone lesion
C
Polyaicular pain
D
M spike present with polyaiculopathy
High-Yield Explanation
Answer is A (Anion Gap Raised) Multiple Myeloma is associaitd with decreased Anion Gap. Hypoalbuminemia Multiple Myeloma and other paraproteinemic states like Waldenstorm's macroglobulinemia Lithium intoxication / Bromide intoxication Decreased Anion Gap is rare / uncommon and occurs due to accumulation of positively charged unmeasured cations which lower the anion gap This is impoant as it may mask a significant anion gap acidosis.

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