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Pediatrics General 34582758

A 2 year old child is brought by parents with history of seizures and developmental delay. He has multiple hypopigmented macules over the back. What is the most probable diagnosis –

A
Neurofibromatosis type 1
B
Tuberous sclerosis
C
Sturge weber's syndrome
D
Linear Sebaceous nevus syndrome
High-Yield Explanation
History of seizures and multiple hypopigmented macules over the back (ash leap patch) suggest the diagnosis of tuberous sclerosis. Criteria for diagnosing tuberous sclerosis Criteria for diagnosis of tuberous sclerosis complex have been revised. The features have been divided into major features and minor features : - Definitive diagnosis ---> Either 2 major features or 1 major plus 2 minor features. Probable diagnosis --> 1 Major plus 1 minor features Possible diagnosis      -->        1 Major feature or 2 or more minor features

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