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Pharmacology Cardiovascular system 3450b6c8

The half-life of Digoxin is

A
24hours
B
40hours
C
48hours
D
60hours
High-Yield Explanation
Digoxin is not extensively metabolized in humans; almost two-thirds is excreted unchanged by the kidneys. Its renal clearance is propoional to creatinine clearance, and the half-life is 36-40 hours in patients with normal renal functionReference: Katzung Pharmacology; 13th edition; Chapter 13; Drugs Used in Hea Failure

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