Baclofen acts as -
High-Yield Explanation
Ans. is 'b' i.e., GABAB receptor agonist There are two types of GABA receptors. 1. GABAA receptor - Intrinsic ion channel --> increases Cl- conductance, blocked by bicuculline, facilatated by benzodiazepines. 2. GABAB receptor - G protein coupled receptor; hyperpolarizes neurones by increasing IC conductance and altering Ca' flux, bicuculline has no effect, blocked by saclofen. o Baclofen acts as an agonist on GABAB receptor.