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Pharmacology General 3356918b

Which of the following is inhibited by Aspirin: September 2010

A
Cyclo oxygenase
B
Lipo oxygenase
C
Phospholipase
D
None of the above
High-Yield Explanation
Ans. A: Cyclo Oxygenase Aspirin also has an antiplatelet effect by inhibiting the production of thromboxane by inhibiting coxl and tx-synthetase, which under normal circumstances binds platelet molecules together to create a patch over damage of the walls within blood vessels. Because the platelet patch can become too large and also block blood flow, locally and downstream, aspirin is also used long-term, at low doses, to help prevent hea attacks, strokes, and blood clot formation in people at high risk for developing blood clots

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