The gene affected in Gilber's syndrome is:
High-Yield Explanation
PARAMETER Syndrome GILBE'S CRIGLER- NAJJAR TYPE I CRIGLER-NAJJAR TYPE II DUBIN-JOHNSON ROTOR'S Incidence 6%-12% Very rare Uncommon Uncommon Rare Gene affected UGT1A1 UGT1A1 UGT1A1 MRP2 Unknown Metabolic defect |Bilirubin conjugation No bilirubin conjugation ||Bilirubin conjugation Impaired canalicular expo of conjugated bilirubin Impaired canalicular expo of conjugated bilirubin Ref: Sleisenger and Fordtran's, E-9, P-326