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Medicine General 3300baa8

The gene affected in Gilber's syndrome is:

A
UGT1A1
B
MRP2
C
Unknown
D
MRP 3
High-Yield Explanation
PARAMETER Syndrome GILBE'S CRIGLER- NAJJAR TYPE I CRIGLER-NAJJAR TYPE II DUBIN-JOHNSON ROTOR'S Incidence 6%-12% Very rare Uncommon Uncommon Rare Gene affected UGT1A1 UGT1A1 UGT1A1 MRP2 Unknown Metabolic defect |Bilirubin conjugation No bilirubin conjugation ||Bilirubin conjugation Impaired canalicular expo of conjugated bilirubin Impaired canalicular expo of conjugated bilirubin Ref: Sleisenger and Fordtran's, E-9, P-326

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