The conjugation of bilirubin to glucuronic acid in the liver
High-Yield Explanation
In liver bilirubin which is a hydrophobic compound is conjugated with glucuronic acid, to make it water soluble. The fuher transpo of bilirubin into bile is an active process Only unconjugated bilirubin elevates in neonatal/hemolytic jaundiceRef: Textbook of biochemistry for medical students, seventh edition, page no: 277