Full 2L QBank
Pathology Chemical mediators in plasma: Kinin system 3295998e

Which of the following is not a pyrogenic cytokine?

A
IL - 1
B
TNF
C
IFN - a
D
IL - 18
High-Yield Explanation
Pyrogens are substances which cause fever. These can be either exogenous or endogenous. The endogenous pyrogens (also called the pyrogenic cytokines) include: IL-1 IL-6 Tumor necrosis factor (TNF) Ciliary neurotopic factor (CNTF) IFN-a (alpha) IL-18 which is a member of IL-1 family does not appear to be a pyrogenic cytokine.

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