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Pathology General 328a48e6

Which of the following is responsible for adhesion of platelets to the vessel wall?

A
Von Willebrand factor
B
Factor IX
C
Fibrinogen
D
Fibronectin
High-Yield Explanation
the Von-Willebrand factor is responsible for adhesion of platelets to the vessel wall. “Endothelial injury allows platelets to contact the underlying extracellular matrix; subsequent adhesion occurs through interactions with von Willebrand factor (VWF), which is a product of normal endothelial cells and an essential cofactor for platelet binding to matrix elements."—

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