Which finding would be present following selective destruction of Seoli cells?

Seoli cells are stimulated by follicle-stimulating hormone (FSH) to secrete the hormone inhibin. Inhibin is a polypeptide hormone with a structure that is similar to that of insulin (i.e., an A chain and a B chain connected by two disulfide bonds). Its physiologic function is to selectively suppress pituitaty release of FSH. Therefore, if Seoli cells are destroyed, plasma levels of inhibin would decrease and plasma levels of FSH would increase as a result of loss of feedback inhibition. Luteinizing hormone (LH) is suppressed by testosterone of Leydig cell origin. Selective destruction of Seoli cells with Leydig cells left intact would have no effect on circulating levels of testosterone or LH. Finally, Seoli cells are vital for normal spermatogenesis. The spermatozoa mature within the folds of the Seoli cells, which provide maturational factors that are required for spermatogenesis.