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Pharmacology General 31dedf87

Addition of which of the following agent can help in elimination of 15-20 tablets of 10 mg dextroamphetamine -

A
Acetazolamide
B
NH4 CI
C
Penicillamine
D
Na HCO3
High-Yield Explanation
Ans. is 'b' i.e., NH4CI Acidification of urine o Basic drugs are more ionized at acidic pH. So, acidification of urine should be done in poisoning of these drugs. o Examples of such basic drugs are morphine, amphetamine, dexfenfluramine. o Acidification of urine is done by iv infusion of arginine hydrochloride followed by ammonium chloride (NH4CI) by mouth.

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