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Biochemistry Proteins and Amino Acids 31cef079

Which of the following amino acid can have o-Glycoxylation linkage in oligosaccharide molecule:

A
Asparagine
B
Glutamine
C
Serine
D
Cysteine
High-Yield Explanation
Ans. C. SerineMajor Classes of Glycoproteins O-linked GlycoproteinO-glycosidic linkage between hydroxyl side chain of serine or threonine and N-acetyl galactosamine is presentN-linked GlycoproteinN-glycosidic linkage between amide nitrogen of asparagine and N-acetyl glucosamine is present.Glycosyl phosphatidylinositol-anchored (GPI-anchored, or GPI-linked) glycoproteinsThird major class of Glycoproteins.They link several proteins to Plasma membrane.Linked to the carboxyl terminal amino acid of a protein via a phosphoryl-ethanolamine moiety joined to an oligosaccharide (glycan), which in turn is linked via glucosamine to phosphatidylinositol(PI).

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