Stage in which disease is easily recognized and high titre of antibodies are found:

Incubation: This period elapsed from invasion of the tissue by pathogens and appearance of clinical features Prodromal stages: Signs and symptoms are not specific for disease. Antibody titre is rising Fastigium: Disease is easily recognized. In this phase high titres (Peak) of antibodies are found Defervescence stage: Body defense mechanisms dominate and patient feels better Convalescence (recovery stage): In convalescence the antibody titres decrease. The patients may act as carrier also