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Pharmacology General 31a711ad

Dineshbhali Shah suffering from AIDS is on Zidovudine, lamivudine and Indnavir therapy. He develops pulmonary tuberculosis for which treatment is to be staed. Which of the following should be avoided in him?

A
Rifampicin
B
INH
C
Ethambutol
D
Pyrazinamide
High-Yield Explanation
Ans. is 'a' i.e., Rifampicin Rifampicin induces metabolism of ritonavir, indinavir and saquinavir, thus it should not be used with these drugs. Rifabutin can be used.

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