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Biochemistry General 31675338

Which of the following enzymes is/are involved in neoglucogenesis all except:

A
Phosphoglycerate kinase
B
Fructose 1, 6-biphosphatase
C
Phosphoglucomutase
D
Pyruvate carboxylase
High-Yield Explanation
C i.e. Phosphoglucomutase- Neoglucognesis (gluconeogenesis) involves all enzymes of glycolysis involved in bidirectional reactions such as phosphohexo isomeraseQ, aldolase, glyceraldehyde 3 phosphate dehydrogenase, phosphoglycerate kinase/mutaseQ, and enolase. Whereas for thermodynamically irreversible reactions of glycolysis, it uses pyruvate carboxylase & phosphoenol pyruvate (PEP) carboxykinaseQ in place of pyruvate kinase; fructose 1, 6 bi phosphataseQ in place of phosphofrctokinase and glucose 6 phosphataseQ in place of hexo/ glucokinase- Phosphoglucomutase is involved in Glycogen metabolismQ not gluconeogenesis.Glucose-6-PO4 ). Glucose - 1- PO4

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