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Anatomy Other topics and Adverse effects 3160fdd5

Regarding the lipid or liposomal formulation of amphotericin B which of the following statements is accurate

A
They are expensive to use than conventional amphotericin B
B
There are more effective in fungal infections than conventional preparations because they increase tissue uptake of amphotericin B
C
They may decrease the niprotoxicity of amphotericin B
D
They have wider spectrum of antifungal activity than conventional formulation of amphotericin B
High-Yield Explanation
Ref-KDT 6/e p758 Newer liposomal preparations of amphotericin B have the following features: Less chances of nephrotoxicity and infusion related reactions Lesser uptake in the tissues like kidney More expensive Similar in efficacy and antifungal spectrum as conventional preparations

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