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Pathology All India exam 315d6326

the above marked structures are seen in a condition where most common cause of death is ?

A
heafailure
B
aspirational pneumonia
C
renal failure
D
neuroparalytic coma
High-Yield Explanation
Alzheimer&;s Disease * The most common cause of Dementia -- Progressive Memory Loss Plus loss in one other area of cognition: * Perception * Attention * Language/Symbols * Judgment * Reasoning * Problem Solving * Interferes with Activities of Daily Living * Other causes (stroke) and mimics (depression) ruled out . PATHOPHYSIOLOGY * Alzheimer&;s disease attacks nerves and brain cells as well as neurotransmitters. * The destruction of these pas causes clumps of protein to form around the brain&;s cells. These clumps are known as &;plaques&; and &;bundles&;. The presence of the &;plaques&; and &;bundles&; sta to destroy more connections between the brain cells, which makes the condition worse. neurofibrillary tangles are seen in brain parenchyma which due to neuronal damage leading to extracellular deposition which is stained with BIELISCHOWSKY STAINING . REF: ROBBINS 10TH ED

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