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Psychiatry General 315ab04d

All the following statement about clozapine are true except -

A
It is used in schizophrenia
B
May precipitate seizure
C
May cause agranulocytosis
D
Extrapyramidal side effects are seen
High-Yield Explanation
Clozapine It blocks D4, 5-HT, and α-adrenergic receptors. Despite of anticholinergic property, it causes hypersalivation. It also blocks H1-histaminic receptors. The important side effects are agranulocytosis & myocarditis. It can induce seizures even in nonepileptics. It causes weight gain and precipitation of diabetes. It does not produce extrapyramidal side effects.

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