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Biochemistry HAEM synth and porphyrias 30e8b85b

Which of the following enzyme of Heme synthesis is located in mitochondria?

A
ALA synthase
B
ALA dehydratase
C
Uroporphyrinogen I synthase
D
Uroporphyrinogen decarboxylase
High-Yield Explanation
First reaction and the last 3 reactions of heme synthesis take place in the mitochondria. The rest of them takes place in cytosol. Figure: Heme synthesis occuring in mitochondrion & cytosol

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