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Medicine Oncology 30d9b218

All of the following immunosuppressives cause profound myelosuppression except-

A
Sirolimus
B
Cyclosporine
C
Azathioprine
D
Mercaptopurine
High-Yield Explanation
Pharmacokinetics, mechanism of action, clinical efficacy in organ transplants, adverse effects, and dosage and administration of cyclosporine, a new immunosuppressant, are reviewed .Cyclosporine acts by blocking T-lymphocyte function without causing myelosuppression Ref Harrison 20th edition pg 578

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