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Medicine Oncology 30c55927

A 30-year-old man presents to the emergency department for assessment of new symptoms of hematuria. The physical examination is normal except for an elevated blood pressure of 164/94 mm Hg. An ultrasound of the kidneys reveals multiple renal cysts in both kidneys. His father had a similar condition. Which of the following is not associated with this syndrome?

A
liver cysts
B
intracranial aneurysms
C
autosomal dominant inheritance
D
rheumatoid arthritis (RA)
High-Yield Explanation
RA is not associated with polycystic kidney disease. It has an autosomal dominant inheritance and about 50% developed renal failure by age 60 years. Cysts are also seen in the liver (more common) and pancreas. Also 5% - 10% of asymptomatic patients can have cerebral aneurysms. Renal transplantation is utilized in end-stage renal failure (ESRF). The transplanted kidney cannot be affected by the disease.

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