Pathology Misc. (R.B.C) 30b21153

In HbM the position of point mutation

b chain, 87th codon, Histidine - Tyrosine

a chain, 87th codon, Histidine - Tyrosine

b chain, 6th codon, Glutamine - Valine

b chain, 6th codon, Glutamine - Lysine

High-Yield Explanation

Ans. (b) a chain, 87th codon, Histidine - Tyrosine(Ref: Wintrobes 12th ed 1060-1070)M (met) hemoglobins are characterized by heme-iron oxidation and result in cyanosis.HbM Iwate (HBA 87th position his - tyr)

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In HbM the position of point mutation

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