Full 2L QBank
Microbiology Immunology 30b1b21e

Bence Jones proteins are best described as:

A
u chains
B
g chains
C
Kappa and Lambda chains
D
Fibrin split products
High-Yield Explanation
Ans. is 'c' i.e., Kappa and Lambda chains (Ref: Ananthanarayan, 9th/e, p. 99 and 8th/e, p. 100)* A Bence Jones protein is a monoclonal globulin protein or immunoglobulin light chain found in the urine, with a molecular weight of 22-24 kDa. Detection of Bence Jones protein may be suggestive of multiple myeloma or Waldenstrom's macroglobulinemia.* Bence Jones proteins are light chains of immunoglobulins so may occur as Lambda or Kappa forms, but in any other patient the chain is either Kappa or Lambda, never both.

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