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Gynaecology & Obstetrics General 3095cfce

Which of the following is an impoant tumour marker in the diagnosis of endodermal sinus tumour: March 2011

A
HCG
B
Ca-125
C
LDH
D
Alpha FetoProtein
High-Yield Explanation
Ans. D: Alpha Feto Protein Endodermal sinus (yolk sac) tumour is thought to originate from a multiple potential embryonal tissue as a result of selective differentiation of yolk sac structures. This explains why the tumour is rich in alpha-fetoprotein and alphal antitrypsin

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