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Biochemistry General 3039efbb

Which of the following is rate limiting enzyme of fatty acid synthesis

A
Acetyl CoA carboxylase
B
Carnitine acyltransferase I
C
HMG CoA Synthase
D
HMG CoA reductase
High-Yield Explanation
Acetyl CoA Carboxylase is the rate limiting enzyme. It is activated by Insulin, Citrate. Inhibited by Glucagon, Palmitoyl CoA. It converts acetyl CoA to Malonyl CoA. Carnitine acyltransferase I is the rate limiting enzyme for fatty acid oxidation. HMG CoA synthase is RLE for Ketone body synthesis. HMG CoA reductase is RLE for Cholesterol synthesis.

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