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Pharmacology Cell Wall Synthesis Inhibitors 2fd13a1a

All of the following statements regarding development of resistance against penicillins is true EXCEPT?

A
Bacteria may develop inactivating enzymes called penicillinases.
B
Bacteria may develop altered penicillin binding proteins
C
Bacteria may develop alternate metabolic pathway
D
Bacteria may become less permeable to penicillins
High-Yield Explanation
Major methods of development of resistance to penicillins are: Development of beta lactamases like penicillinases e.g. many staphylococci Development of altered PBPs e.g. in MRSA Decreased permeability to penicillins e.g. in low level resistance to gonococci

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