Streptococcal GN is best diagnosed by -

Ans. is 'b' i.e., AntiDNAse; 'c' Antihyaluronidase . "Antistreptolysin - 0 (ASO), anti DNAase B, antihyaluronidase, anti-NADase are elevated in more than 95% cases of PSGN (Post streptococcal glomerulonephritis) secondary to Pharyngitis". - API . Anti DNAase B and antihyaluronidase are elevated in more than 85% cases of PSGN following skin infection". - API . So PSGN can be diagnosed by anti DNAase B and antihyaluronidase because these antibodies are elevated after skin infection as well as after pharyngitis, while ASO is not elevated after skin infection.