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Medicine General 2f610a91

True Statement about Pneumocystic Jiroveci is

A
Often associated with CMV infection
B
Usually diagnosed by sputum exammination
C
Infection occurs only in immunocompromised patients
D
Always associated with Pneumatocele
High-Yield Explanation
Ans. is 'b' i.e., Usually diagnosed by sputum exammination Pneumocystic Jiroveci is the new nomenclature for human infection with Pneucystis carinii. The term Pneumocystic carinii is used only for pneumocytis infection in rats. Pneumocystic infection in rats -p Pneumocystis carinii. Pneumocystic infection in man --> Pneumocystic Jiroveci Pneumocystis is an oppounist pathogen that is an impoant cause of pneumonia. The host factors that predispose to the development of pneumocystic are defects in cellular and humoral immunity. Pneumocystic Jiroveci may infect an immunocompetent individual but the disease is manifested only when the patient is immunocompromised. Pneumocystis Jiroveci does not cause disease in the absence of immunosuppression. The persons at risk for developing pneumocytosis. HIV patient with CD4 count < 200/m1 Patients receiving immunosuppressive therapy. Organ transplantation. Children with primary immunodeficiency Premature malnourished children. Diagnosis of pneumocystosis Diagnosis of pneumocystic pneumonia is based on specific identification of the organisms. Various methods used are - Sputum examination The initial method of diagnosis for pneumocystic infection is sputum examination. Routine sputum samples are often inadequate therefore sputum sample should be obtained by induction with hypeonic saline. Histopathological staining of sputum is done to identify the organism. Bronchoalveolar Lavage Sputum examination may be the initial method of diagnosis of Pneumocystic pneumonia. But the mainstay of the of diagnosis of pneumocystic pneumonia is bronchoalveolar lavage.

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