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Physiology Cardiovascular system 2f2dbe9f

Which of the following helps in bridging the fibrin in a clot and stabilizes the clot?

A
Factor XIII
B
Factor V
C
Factor VII
D
Factor III
High-Yield Explanation
The fibrin is initially a loose mesh of interlacing strands. It is conveed by the formation of covalent cross-linkages to a dense, tight aggregate (stabilization). This latter reaction is catalyzed by activated factor XIII and requires Ca2+.Factor V is required for formation of prothrombin activatorFactoVII is required for the activation of factor XFactor III is also required for formation of prothrombin activatorRef: Ganong's Review of Medical Physiology Twenty-Third Edition Page No:532

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