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Biochemistry General 2eaa1026

Which of the following statements is true regarding enzyme inhibition?

A
Sulfonamides inhibit folate reductase irreversibily
B
Ethanol inhibits aldehyde dehydrogenase when used in methanol poisoning
C
Acetylcholinesterase inhibition by malathion can be reversed by increasing the levels of Acetylcholine
D
Fluoroacetate competitively inhibits Aconitase
High-Yield Explanation
Sodium flouroacetate compete with acetic acid and form flouroacetic acid .This inhibit TCAcycle by poisoning aconitase enzyme activity. Ref: Perspective in mycological research by Perspective in mycological research, The encyclopedia of nutrition and good health By Robe A. Ronzio page 436; Medical toxicology By Richard C. Da page 65.
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