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Physiology Misc. 2e3b4631

Platelet function tested by

A
Bleeding time
B
Prothrombin time
C
Clot retraction test
D
Thrombin time
High-Yield Explanation
(A) Bleeding time # Most important screening tests of the primary hemostatic system are> Bleeding time (a sensitive measure of platelet function), and a platelet count.> Latter correlates well with the propensity to bleed. The normal platelet count is 150,000 to 450,000/mL of blood. As long as the count is > 100,000/mL, patients> are usually asymptomatic and the bleeding time remains normal.> Platelet counts of 50,000 to 100,000/mL cause mild prolongation of the bleeding time; bleeding occurs only from severe trauma or other stress.> Patients with platelet counts 50,000/pL have easy bruising, manifested by skin purpura after minor trauma and bleeding after mucous membrane surgery. Patients with a platelet count 20,000/pL have an appreciable incidence of spontaneous bleeding, usually have petechiae, and may have intracranial or other spontaneous internal bleeding

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