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Gynaecology & Obstetrics Infections in pregnancy 2e044778

A fetus born to a mother with history of fever with rash in first trimester of pregnancy shows chorioretinitis, cerebral coical atrophy, cutaneous scarring and bone leg defects. Most probable cause is?

A
Maternal rubella
B
Maternal varicella
C
Maternal CMV
D
Maternal toxoplasma
High-Yield Explanation
Maternal varicella during the first half of pregnancy may cause congenital malformations by transplacental infection called congenital varicella syndrome Eye defects: Microphthalmia, chorioretinitis, cataracts Neurological: microcephaly, cerebral coical atrophy, neurological dysfunction of bladder and bowel sphincters Cutaneous: scarring in dermatomal origin Bony defects: limb hypoplasia

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