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Medicine AIIMS 2017 2e0115a1

Asymptomatic hep B is common in 2-3% normal population, but there is increased risk of transmission into hepatocellular carcinoma. Why?

A
Inability to induce inflammation to remove the organism
B
High level of transaminases
C
High rate of proliferation of virus
D
Integration of viral DNA with host DNA
High-Yield Explanation
Option A- Explanation for carrier stage Option C- Refers to high infectivity of the virus so basically higher chances of infection but not cancer. Option D- This leads to inhibition of apoptosis so might cause cancer of liver (HCC)

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